A head-on collision in Caledon has sent four people to the hospital on Monday evening, one in critical condition.

Provincial police have closed Highway 10 between Olde Base Line Road and Charleston Side Road for the two-vehicle crash that destroyed both vehicles.

Hwy 10 crash

A driver of one of the vehicles suffered life-threatening injuries while three other people are being treated in hospital for serious injuries.

Provincial police say both drivers, from Toronto and Mississauga, were travelling with suspended licences at the time of the crash.

Caledon OPP is investigating and asking witnesses to the collision to come forward.